David Tennant, a Scottish actor celebrated for his extensive work in theatre, film, and television, has also built a notable career as a voice actor, contributing to various animated projects, including the anime series Eden. In the 2021 Netflix original anime Eden, Tennant voices the character E92 in the English-language dub. E92 is a robot whose primary function is harvesting apples. Along with another robot, A37, he discovers a human baby in a cryogenic pod and makes the pivotal decision to raise her in secret, defying the rules of the robot-dominated city. This role places him within a production that features a notable cast including Rosario Dawson and Neil Patrick Harris.

Beyond this specific anime credit, Tennant's voice work frequently intersects with genres and styles popular within anime and animation fandom. He is widely recognized for voicing the ancient droid professor Huyang in the Star Wars animated series The Clone Wars, a role he later reprised in the live-action series Ahsoka. His performance as Huyang earned him a Daytime Emmy Award for Outstanding Performer in an Animated Program in 2013. Tennant has also lent his voice to the DreamWorks animation franchise How to Train Your Dragon as the character Spitelout, and voiced the Fugitoid in the Teenage Mutant Ninja Turtles animated series. In 2018, he joined the cast of gen:Lock, an anime-influenced, 3D-animated series from Rooster Teeth, voicing the character Dr. Rufus Weller, also known as Doc. His work in animation also includes the lead role of Scrooge McDuck in the 2017 revival of the classic series DuckTales.