Isabella Grothe is a German actress who is primarily known for her extensive work as a voice actress, providing the German dubbing for numerous characters in international film and television productions. Her career encompasses a significant body of work in the dubbing of live-action series and films, as well as a substantial number of roles in anime and animated series.

As a voice actress, Grothe has built a comprehensive portfolio that spans several decades. In the realm of live-action dubbing, she is particularly recognized for lending her voice to Annette O'Toole as Martha Kent in the series Smallville, to Betsy Russell as Jill Tuck in the Saw film series from part three to six, and to Patricia Richardson as Jill Taylor in the German broadcast of Home Improvement. She also voiced Isobel Crawley, later Merton, in the series Downton Abbey.

In the field of anime and animation, Grothe has voiced a wide array of characters. Among her notable roles is Tsubone, a secondary antagonist in the Netflix animated series Aggretsuko, where she is the German voice for the character originally played by Maki Tsuruta. She also voiced Coda Lovell in the film Eureka Seven - good night, sleep tight, young lovers. In the historical anime series Emma: A Victorian Romance, she took on the role of Kelly Stowner, the kind former governess who becomes a maternal figure to the protagonist. Another of her credits includes the role of Margrets Tante in the anime adaptation of The Yearling.

Her other extensive voice work in anime includes the role of Chiyo in the long-running series Naruto Shippuden, Queen Victoria in Black Butler: Book of Circus and Black Butler: Book of the Atlantic, and roles in series such as Little Witch Academia, Sherlock Hound, and Treasure Island. Her career demonstrates a consistent and prolific presence in the German dubbing industry, contributing voices to both major international blockbusters and a diverse range of animated productions. She is the mother of German voice actress Kristina von Weltzien.