Mark Hamill is an American actor widely recognized for his extensive and influential work in voice acting, a career that runs parallel to his iconic live-action role as Luke Skywalker in the Star Wars franchise. His voice acting repertoire is vast, spanning animation, video games, and film, and includes several notable contributions to projects that fall within the broader spectrum of anime and animated features with a strong anime influence.

Within the realm of anime, Hamill is perhaps best known for his role as Colonel Muska in the English-language Disney dub of Hayao Miyazaki's classic Studio Ghibli film, Castle in the Sky. He provided the voice for the film's primary antagonist, a government agent whose true goal is to seize control of the legendary flying city of Laputa. This performance is part of a larger association with Studio Ghibli's works for Hamill; he also voiced the Mayor of Pejite in the 2005 Disney dub of Nausicaä of the Valley of the Wind. Decades later, he continued his involvement with the esteemed studio by taking on a voice role in Hayao Miyazaki's The Boy and the Heron.

Another example of Hamill's work in animation that appeals to an adult anime audience is his role in Dante's Inferno: An Animated Epic. Released in 2010, this direct-to-video film is a companion piece to the Electronic Arts video game and presents a stylized, action-oriented adaptation of the first part of Dante Alighieri's Divine Comedy. Hamill is part of the voice cast for this animated feature, which blends various animation styles to depict Dante's journey through the nine circles of Hell.

Beyond these specific credits, Hamill's voice acting career is marked by a high degree of versatility and a particular talent for portraying villains. He is most celebrated for his definitive portrayal of the Joker in the DC Animated Universe, beginning with Batman: The Animated Series in 1992, a role he has reprised numerous times across various series and films. This success led to a wide array of other voice roles, including Fire Lord Ozai in Avatar: The Last Airbender, the Hobgoblin in Spider-Man: The Animated Series, and Skips in Regular Show. His contributions to the craft have been recognized with nominations from the Annie Awards and a win at the British Academy Games Awards for his performance in the video game Batman: Arkham City.