Manuela Origuella is a Brazilian voice actor known for her work in anime dubbing, providing Portuguese voices for a range of characters in popular series. Her roles demonstrate a versatility across different genres, from action-oriented titles to romantic comedies.

Origuella has been credited with several significant roles in anime localized for the Brazilian market. She is recognized for voicing Saiko Yonebayashi in both seasons of Tokyo Ghoul:re. She also voiced Isabel Magnolia in the Attack on Titan: No Regrets original anime video. Another notable role is Operator 21O in the anime adaptation of NieR:Automata Ver 1.1a. In the romantic comedy genre, she voiced Erika Amano for the Brazilian dubbing of the second season of A Couple of Cuckoos. Her work also includes the character Monika Kaniyashiki in the second season of My Hero Academia: Vigilantes. Additional credits from the Anime News Network encyclopedia list her roles in series such as Assassination Classroom as Rinka Hayami, as well as appearances in Blue Reflection Ray, Deca-Dence, Rumble Garanndoll, and Super Cub.

Based on available information, Origuella frequently works with Dubrasil, a dubbing studio based in São Paulo. Her work on A Couple of Cuckoos was directed by Fábio Campos at this studio, and the dubbing for NieR:Automata Ver 1.1a was also produced there under the direction of Guilherme Marques and Jonas Falcão. This indicates a professional relationship with the studio and its regular directors and cast. Her credits often place her alongside other prominent Brazilian voice actors such as Azumi Botsu, Raíssa Bueno, and Daniel Figueira, suggesting recurring collaborations within the industry.

A notable aspect of Origuella's career is her involvement in dubbing for major international anime franchises. Her participation in globally popular series like Tokyo Ghoul, Attack on Titan, and NieR:Automata highlights her contribution to bringing these stories to Portuguese-speaking audiences in Brazil. Her work on NieR:Automata Ver 1.1a was part of a high-profile anime release that generated significant interest among fans. Similarly, her casting in the second season of My Hero Academia: Vigilantes places her within the context of one of the most popular contemporary anime series.