Kyohei Natsume is a Japanese voice actor from Ibaraki Prefecture, born October 10, who is affiliated with the talent agency VIMS. He has built a career in anime television series and video games, taking on a variety of supporting and lead roles since the early 2020s.

Natsume's filmography includes a range of characters in prominent anime series. He is known for roles such as Nerd A in Loner Life in Another World, the Producer in The iDOLM@STER SHINY COLORS, and Zhores Rimsky in Irina: The Vampire Cosmonaut. He has also had guest or recurring roles in major productions, appearing as a character in Street Fighter 6, a Bulgasario in Tower of God, and a minister in That Time I Got Reincarnated as a Slime. His other credits include parts in series such as Combatants Will Be Dispatched!, Shy, Blue Box, and Sakamoto Days.

A significant recent role for Natsume is his portrayal of the lead character Akito Oota, the expressive male protagonist, in the 2025 romantic comedy anime television series Inexpressive Kashiwada and Expressive Oota. The series, produced by Studio Polon, aired from October to December 2025. He also had an extensive recurring role in Yu-Gi-Oh! Go Rush!!, voicing the characters Ofuruno Jaji and Furinto across 27 episodes from 2022 to 2025.