Xolo Maridueña has established himself as an actor in both live-action and voiceover work, with a growing presence in the world of animation and English dubs of popular anime series. He was born on June 9, 2001 in Los Angeles, California, and began his professional acting career in 2011 at the age of eleven. He is known for his multi-ethnic heritage, having Mexican, Cuban, and Ecuadorian ancestry.

Within the anime and animation voice acting space, Maridueña is recognized for several key roles. He provides the English voice for Heisuke Mashimo in the series Sakamoto Days. He also voices the character Dropkick in the adult animated superhero series Invincible. In 2022, he voiced Aqua Agua in an episode of the anthology series The Boys Presents: Diabolical, which is set in the anime-influenced world of The Boys franchise. The same year, he began voicing Snowy the Snowcrawler in the animated series Batwheels. Other voice credits include roles in Cleopatra in Space as Zaid, Victor and Valentino as Andres, Fast & Furious Spy Racers as Lucas, and Moon Girl and Devil Dinosaur as Kid Kree.

Contrary to the initial prompt stating he plays Portgas D. Ace in the anime film One Piece: The Battle of Alabasta, search results consistently indicate that Maridueña has been cast to portray Ace in the live-action Netflix adaptation of One Piece, specifically for the third season covering the Alabasta arc. This is a live-action role rather than an anime voice acting credit. He has publicly addressed this casting, noting that joining the One Piece production was a personal dream.

Notable achievements in his voice acting career include being cast in major studio animated features. He joined the ensemble voice cast of The Smurfs Movie in April 2024 and is also scheduled to voice a role in the animated film Blue Beetle, reprising his live-action role as Jaime Reyes for an animated production. Additionally, he has a voice role announced for the animated series Primos. Beyond voice acting, Maridueña is widely recognized for his starring role as Miguel Diaz in the Netflix series Cobra Kai and as the title character in the DC film Blue Beetle, which marked a significant moment for Latino representation in superhero cinema. He also co-hosts a podcast titled Lone Lobos.