Tomomi Seo is a Japanese actress and voice actor born on November 21, 1969, in Toyama Prefecture, Japan. She is affiliated with the theatre company Super Eccentric Theater (SET). Her height is recorded as 160 cm, and her blood type is A. She is a graduate of Toyama Prefectural Toyama Minami High School. Her known hobbies include taking walks and practicing classical ballet.

Seo is recognized for her work in anime, with one of her most prominent voice roles being Masami Ooshige in the 2002 series Looking for the Full Moon (also known as Full Moon o Sagashite). In this series, she portrays the manager of the main character, Mitsuki, a role in which she acts as a supportive and protective guardian figure. Her other anime voice credits include the role of Tsubaki Seo in Saint October (2007), a cameo as a fairy in Sugar Sugar Rune (2005), Announcer Ando in Eyeshield 21 (2005), and a role in an episode of Kochira Katsushika-ku Kameari Kōen-mae Hashutsujo. She also provided a voice for the series Mushishi.

Beyond voice acting, Seo has appeared in live-action television dramas. Her roles include parts in the long-running series Aibō (Partners) in 2018 and 2021, as well as a performance in the 2010 drama Ōgon no Buta (Golden Pig). Her film appearances include roles in the movies Gogo no Yuigonjo (Afternoon's Last Will, 1995) and Bokutō Kidan (1992). She has also performed on stage, making her debut in the play DIRT and appearing in the musical Bishōjo Senshi Sailor Moon in 1996, where she played the role of Sailor Tin Nyanko.