Jean-Christophe Bretignière is a French actor and voice actor known primarily for his work in French-language dubbing of anime and other animated series. His career spans both on-screen live-action roles and extensive voice work, but he is most recognized within the anime community for his contributions to French dub productions.

As a voice actor, Bretignière has portrayed a range of characters across several notable anime titles. One of his prominent early roles was Leon Alcott in the series Pet Shop of Horrors. In this gothic mystery anime, his character serves as a detective who becomes entangled with a mysterious pet shop owner, providing a skeptical and determined presence throughout the story. Another key role in his filmography is Bunji Kugashira in the crime drama Gungrave. In that series, he voiced a loyal and high-ranking member of a mafia organization, a character central to the show's themes of friendship and betrayal.

Beyond these two signature roles, Bretignière's anime voice credits include work on a diverse set of series. He contributed voices to Boogiepop Phantom, a psychological horror anime, where he voiced characters including Anno and Yoshiki Tabata. He also performed voice work for the science fiction mystery series Ergo Proxy, taking on the role of the Autoreivs, the robotic beings that populate the show's dystopian world. His other anime credits include supporting roles in Get Backers and the racing anime Initial D, as well as a role in the film Nasu, un Été Andalou.

Bretignière also has a significant association with the long-running series One Piece. He provided the first French voice for the character Pica, a high-ranking officer of the Donquixote Pirates known for his unique and dissonant high-pitched voice. This role represents one of his more high-profile recurring parts in a major franchise. His body of work principally centers on French dubbing productions, and he does not typically appear in original Japanese-language casts.