"Lady Blue" is a 1980s anime series set in a futuristic, dystopian world where society is plagued by corruption, crime, and environmental decay. The narrative centers on Lucy, a skilled and determined private investigator who operates in a sprawling, neon-lit metropolis. Lucy, also known by her alias "Lady Blue," is a former police officer who left the force after becoming disillusioned with its systemic inefficiency and moral compromises. She now works independently, taking on cases that often involve uncovering conspiracies, solving crimes, and confronting powerful adversaries.

The series begins with Lucy being hired to investigate the disappearance of a young woman, which leads her into a web of intrigue involving a powerful corporation. As she delves deeper, she uncovers a sinister plot tied to illegal human experimentation and the exploitation of marginalized communities. Throughout her investigation, Lucy faces numerous challenges, including corrupt officials, ruthless mercenaries, and her own personal demons. Her past as a police officer is frequently referenced, revealing a traumatic event that shaped her current worldview and fueled her relentless pursuit of justice.

Lucy is portrayed as a complex protagonist, balancing her tough, no-nonsense demeanor with moments of vulnerability and introspection. Her interactions with other characters, such as her tech-savvy assistant and a former colleague turned informant, add depth to her character and provide insight into her motivations. The series also explores themes of resilience, morality, and the consequences of unchecked power, often through the lens of Lucy's personal experiences and the cases she takes on.

The plot is episodic in nature, with each episode presenting a self-contained case while gradually advancing the overarching narrative. This structure allows for a mix of action, mystery, and character development, keeping the pacing dynamic and engaging. The series concludes with a climactic confrontation that ties together the central mystery, offering resolution to Lucy's journey while leaving room for interpretation regarding the broader societal issues it addresses.