"Nmeneko" centers on a young girl named Neko, who discovers she has the ability to transform into a cat. This transformation occurs unpredictably, often triggered by stress or strong emotions, and complicates her daily life. Neko lives in a small, rural town where supernatural occurrences are rare, making her condition both a mystery and a source of isolation. Her only confidant is her childhood friend, Haru, who supports her despite his initial skepticism about her abilities.

The narrative explores Neko’s struggle to balance her dual identity while navigating the challenges of adolescence. As she begins to uncover the origins of her powers, she learns of an ancient legend tied to her family lineage, suggesting that her transformation is linked to a long-forgotten pact between humans and feline spirits. This revelation draws the attention of a mysterious organization seeking to exploit her abilities for their own purposes, forcing Neko to confront both external threats and her own insecurities.

Throughout the series, Neko’s relationships with those around her deepen, particularly with Haru, who becomes increasingly involved in her quest for answers. The story also introduces other characters with unique connections to the supernatural, including a reclusive historian who aids Neko in understanding her heritage and a rival figure with similar transformative abilities. The plot weaves together themes of identity, belonging, and the tension between human and animal instincts, culminating in a climactic confrontation that tests Neko’s resolve and her understanding of her place in the world.