"Ichigeki Sacchu!! HoiHoi-san" is a short-form anime series that blends comedy, science fiction, and action. The narrative centers around HoiHoi-san, a highly advanced combat robot designed to exterminate alien cockroaches threatening humanity. Despite her formidable capabilities, HoiHoi-san is packaged and sold as a figurine, leading to a series of absurd and humorous situations as she is purchased by unsuspecting consumers who are unaware of her true purpose.

The story unfolds as HoiHoi-san is activated by her new owner, a young girl named Misato. Misato initially treats HoiHoi-san as a toy, but the robot’s programming compels her to prioritize her mission of eradicating the alien cockroaches. This creates a clash between her deadly efficiency and the mundane, everyday life of her owner. The alien cockroaches, known as Gokiburi, are intelligent and resourceful, often devising elaborate schemes to counter HoiHoi-san’s attacks. The series features a mix of over-the-top action sequences and comedic moments, as HoiHoi-san’s relentless pursuit of the Gokiburi disrupts Misato’s life and surroundings.

HoiHoi-san’s design is both cute and menacing, with her small, doll-like appearance contrasting sharply with her arsenal of weapons and combat skills. Misato serves as the human anchor of the story, providing a relatable perspective as she grapples with the chaos caused by HoiHoi-san’s presence. The Gokiburi, despite being the antagonists, are portrayed with a degree of humor, often engaging in exaggerated and comedic tactics to evade HoiHoi-san.

The series is episodic, with each installment focusing on HoiHoi-san’s encounters with the Gokiburi and the resulting fallout. The tone is lighthearted, with a focus on slapstick comedy and exaggerated action. Despite its short runtime, the series effectively balances its sci-fi premise with comedic elements, creating a unique and entertaining narrative. The interplay between HoiHoi-san’s single-minded mission and Misato’s attempts to maintain a normal life drives much of the humor and conflict, making for a fast-paced and engaging viewing experience.