In the anime Pac-Man and the Ghostly Adventures, Clyde is a member of the Ghost Gang, a group of four spirits who secretly befriend the hero Pac-Man. His physical appearance distinguishes him from his companions; he is the largest member of the group, with a rounded, substantial form colored a warm orange. He has purple eyes, a small curl of hair on top of his head, and tentacle-like appendages instead of traditional limbs, giving him a unique and somewhat gentle look within the series.

Personality-wise, Clyde is portrayed as the most caring and sensitive member of the Ghost Gang. While he may come across as dim-witted or unintelligent at times, this often belies an unexpected depth of character. He has a soft spot for sweet and adorable creatures like Fuzbits, and frequently acts as a peacekeeper when his fellow ghosts, particularly the hot-headed Blinky and the excitable Inky, begin arguing or fighting. His nature is passive and nurturing, and he occasionally offers surprising pearls of wisdom, suggesting that he may be more intelligent than he lets on in his typical, slower manner of speaking. This gentle disposition is a key part of his role within the group, making him the moral compass and a source of emotional support for his friends. He is so emotionally sensitive that when he becomes extremely upset, he has been known to physically split in half.

Clyde's primary motivation is tied to the central goal of the Ghost Gang. Having been separated from their physical bodies and relegated to the Netherworld, he, along with Blinky, Inky, and Pinky, seeks redemption. They hope that by secretly helping Pac-Man protect Pac-World from the antagonistic Lord Betrayus, they will eventually earn the right to be restored to their corporeal forms and live again. This desire for a second chance at life drives their actions throughout the series, leading them to work against their nominal ruler, Betrayus, in a covert alliance with Pac-Man.

In the story, Clyde and his fellow ghosts maintain a public facade of serving Lord Betrayus, but their true allegiances lie with Pac-Man and his friends. This secret friendship forms a core part of the series' narrative, as the Ghost Gang frequently provides aid, information, and occasional comic relief while hiding their collaboration from the other denizens of the Netherworld. Clyde's role within this alliance is that of a loyal and steadfast supporter. He shares a particularly close bond with the pink ghost Pinky, and the two are often seen together. He also shares a notable characteristic with Pac-Man: a large appetite, which serves as a humorous point of connection between them.

Clyde's character in this series represents a significant departure from his traditional role in the broader Pac-Man franchise, where he is often a cowardly or slow-witted enemy. His development is not marked by a dramatic change in personality, but rather a consistent demonstration of his inherent goodness. Throughout the series, he remains the kind-hearted giant of the group, whose simple wisdom and gentle nature prove invaluable. While he may not be the sharpest or most cunning member of the Ghost Gang, his loyalty, emotional sensitivity, and willingness to keep the peace make him a crucial ally to Pac-Man and a beloved member of the team.

In terms of notable abilities, Clyde, like other ghosts, possesses the power of flight and intangibility. He is also shown to have surprising physical strength; in some video game adaptations of the series, he is depicted as the strongest of the Ghost Gang, being the only one capable of flying upwards while carrying Pac-Man's weight. His large size, rather than being a hindrance, often proves to be an asset in these situations. His physical quirk of splitting in half when upset is another unique, if involuntary, trait.