Miko Saegusa is a supporting character in the anime Kamichu!. She is the younger sister of Matsuri Saegusa and lives with her family at Raifuku Shrine, where her father serves as a Shinto priest. Miko is depicted as a shy and reserved girl who is notably polite and respectful toward everyone she meets. She takes on the responsibility of cooking for her household and regularly helps maintain the shrine, assisting with various duties to keep it running smoothly.

Miko possesses the ability to see and communicate with spirits, including gods and other supernatural beings. This gift allows her to interact with the divine realm in ways that most ordinary humans cannot. She has a quiet crush on Yashima, the god of the shrine, and is often seen speaking with him, showing a gentle and earnest affection for the deity. Her motivations are largely rooted in supporting her family and the shrine, as well as nurturing her personal connection to the spiritual world.

In the story, Miko appears as a calm and supportive presence among the main cast, which includes her sister Matsuri, the newly divine Yurie Hitotsubashi, and their friends. Her relationship with Matsuri is close, with Miko often helping her older sister with shrine-related tasks and household matters. She also interacts warmly with Yurie and other characters, though her shy nature keeps her somewhat in the background. Her development is subtle; she remains consistently kind and dutiful throughout the series, with moments that highlight her growing confidence in her spiritual perception and her quiet devotion to Yashima. Her notable ability to see spirits is integral to several episodes, as it allows her to perceive events and beings that others cannot, further grounding the series' supernatural themes.