Graham serves as US Army General and Chief of Staff, maintaining a composed and authoritative demeanor. He prioritizes national security and the military's reputation. During the White House bio-terror incident involving zombie attacks, Graham oversees the military response, initially focused on containment and protecting the President.

Later investigations uncover Graham's deeper involvement in classified operations. Years earlier, he commanded covert US military operations in Penamstan. During this conflict, Graham authorized deploying experimental bio-organic weapons (BOWs) derived from the T-virus against enemy forces, causing significant collateral damage and civilian casualties.

To conceal the unauthorized BOW use and resulting atrocities, Graham engineered a cover-up, silencing personnel involved in the Penamstan operations. He continued secret BOW development projects under the guise of national defense, aiming to create controllable bioweapons for military application.

Graham perceives these actions as necessary for American strength and security, deeming extreme measures vital. He attempts to eliminate individuals uncovering the Penamstan truth, targeting former operatives and investigators like Jason. His primary goal becomes protecting the secret and ensuring his BOW program's survival.

Evidence of Graham's command decisions in Penamstan and his subsequent cover-up operations is ultimately uncovered, directly implicating him in war crimes and illegal bioweapons development. Following this exposure, federal authorities arrest Graham, ending his military career.