Konoka Konoe, also called Kono-chan, Ojou-sama, or Regina Medicans, stands as a central figure. She occupies the thirteenth position in Japanese alphabetical order within Mahora Academy's class 2/3-A. Her lineage defines her background: granddaughter of Mahora's Dean, Konoemon Konoe, and daughter of Eishun Konoe, chief of the Kansai Magic Association. Her mother was the daughter of the Kantō Magic Association's head; their arranged marriage eased tensions between the rival associations. Despite this heritage, she remained deliberately unaware of her magical potential and family's mystical connections for a normal life, discovering her abilities only during a trip to Kyoto. Konoka displays a cheerful, nurturing, and slightly naive personality. She acts as a mediator within her social circle, particularly as the roommate of Asuna Kagurazaka and Negi Springfield. She often assumes a maternal role, cooking and caring for Negi while tolerating Asuna's sharp comments. Academically intelligent but unassuming, she participates in clubs like the Fortune-Telling Club, where she serves as president, and the Library Exploration Club alongside Nodoka Miyazaki, Yue Ayase, and Haruna Saotome. Her interests encompass fortune-telling, the supernatural, and cooking; she dislikes separation from friends. Her closest relationship is with Setsuna Sakurazaki, her classmate and guardian from Kyoto. Their childhood friendship fractured when Setsuna blamed herself for failing to prevent Konoka's fall into a stream, leading to years of avoidance. This distance ended during the Kyoto incident, where Konoka's latent magical abilities awakened to heal Setsuna's severe injury, leading to reconciliation. Setsuna often struggles with romantic feelings, especially as Konoka faces repeated omiai proposals from her grandfather; Konoka has stated she is not ready for serious romantic commitments. Magically, Konoka possesses immense potential as a healer. Her powers first manifested subtly during a shopping trip with Negi and fully emerged in Kyoto to heal Setsuna. Later, to save Negi from petrification, she formed a Pactio with him via a direct kiss, becoming his fourth partner. Her artifact is an Onmyouji outfit with fans capable of healing any injury within three minutes. Under Negi and Evangeline's tutelage, she learned basic spells and honed her restorative magic, resembling a "Seer" from the Final Fantasy series when using her abilities. Her healing prowess was later utilized openly during events like the Mahora Festival's infirmary operations. In broader conflicts, Konoka was briefly kidnapped during the Wilhelm incident but escaped to aid Negi and rescue Setsuna. During the Mahora Festival, she was transported to a future where magic was publicly revealed, participating in battles before returning to prevent that timeline. In the sequel *UQ Holder!*, a flashback in Chapter 147 depicts a young woman resembling Konoka present at the birth of Touta Konoe, suggesting a familial connection, though her exact role—whether Konoka herself or a descendant—remains unconfirmed. Throughout her journey, Konoka evolves from an oblivious student into a confident healer, balancing her innate kindness with the responsibilities of her magical heritage. Her relationships, particularly with Setsuna and Negi, remain central to her development, emphasizing loyalty and growth amidst supernatural challenges.