Megumi Amano is Amano Jyaku's sister, hailed within her narrative as "the strongest female of the three realms." She arrives to aid her brother against the Chōjin (Overfiend) and expresses a strong sexual desire for the Overfiend upon meeting its perceived host, Nagumo Tatsuo. Significant differences exist between her manga and anime portrayals. In the manga, she is a manipulative antagonist who tricks men into sex to later frame them for rape or transforms into her beast form to cannibalize them. She develops a petty grudge against Itō Akemi due to Nagumo's preference for Akemi, even attempting to kill her by summoning the demon king of the sea. Her manga personality is more tomboyish, and she often wears masculine clothing. Conversely, the anime adaptation removes most malicious traits, depicting her as kinder, more empathetic, and feminine. Her anime role is expanded, lacking the sociopathy and cannibalism. An anime-exclusive element is her romantic subplot with Nagumo's cousin, Takeaki Kiryū. This relationship ends tragically when she is forced to kill Takeaki during the battle against Münchhausen II atop the Shinjuku skyscrapers, an event that deeply affects her. Physically, she has cyan hair, blue eyes, and a distinctive style where her skirt rarely covers her underwear, frequently resulting in panty shots. She possesses "Super Toughness," a trait consistently protecting her from the extreme violence and violations affecting others, aiding her survival. Despite combat abilities, she often loses to named antagonists and experiences violations, placing her in a "Faux Action Girl" category where she excels against lesser foes but struggles against primary adversaries. In *Urotsukidōji II: Legend of the Demon Womb*, she takes a central role as her romance with Takeaki intertwines with Faust Münchhausen II's machinations to revive the Kyō-Ō using Takeaki as its host. Her character development involves grappling with her feelings for Takeaki amidst the surrounding chaos and conflict.