Nene Nishidera, who uses the stage name Nene Saionji while working at Café Liebe, is a veteran member of the café staff. She was scouted by manager Mai Koshiba at a lesbian bar and became the third employee of the establishment, originally working as a waitress in the salon. Her real surname is Nishidera, with Saionji being the name she uses during performances. She has silver-blue or light grey hair and green or violet eyes.

Her personality is generally calm, though she can come across as aloof and cold at times. This outward demeanor masks a more emotionally complex interior. Her story is driven by unspoken romantic feelings, jealousy, and impulsive decisions. She once formed a sister bond, known as a schwester relationship, with Sumika Chibana. However, romantic complications led to a rift between them, causing Nene to leave her front-of-house position and move to the kitchen, where she now works as the café cook. This shift in role reflects a retreat from the performance floor due to personal heartbreak and the painful effort to make peace with the past.

Her role in the story is that of a supporting character whose history provides emotional depth to the café's dynamics. Her key relationships include her past bond with Sumika, which remains a source of tension and regret, and her connection to Mai, who recognized her as a suitable fit for the café. Over the course of the narrative, Nene undergoes development centered on confronting her past choices and the unresolved feelings tied to her time as a waitress. She is not a flashy presence but instead offers emotional realism, with her character arc shaped by the consequences of her unspoken love and the difficulty of moving forward. Her notable abilities include her work as a cook, a role she now occupies behind the scenes, and her earlier capacity to perform the aesthetic, class-S romance scenes expected of waitresses at the café.