"Zombie-Bitch SAKINA is in Bitch-girl" is a manga series that blends elements of horror, dark comedy, and supernatural themes. The story centers on Sakina, a high school girl who dies under mysterious circumstances and is resurrected as a zombie. Unlike traditional zombie narratives, Sakina retains her intelligence and personality but is cursed with an insatiable hunger for human flesh. This condition complicates her attempts to reintegrate into her former life, as she struggles to conceal her undead nature while navigating the social dynamics of high school.

The plot explores Sakina's dual existence as both a predator and a victim. Her transformation forces her to confront the darker aspects of her humanity, including her relationships with classmates and her own moral dilemmas. As she grapples with her new reality, Sakina encounters other supernatural entities, including a rival zombie and a mysterious figure who may hold the key to her condition. These interactions drive the narrative forward, creating tension and conflict as Sakina seeks to understand her curse and find a way to coexist with the living.

Key characters include Sakina's best friend, who becomes suspicious of her strange behavior, and a classmate who harbors a secret connection to the supernatural world. The series also features a range of antagonists, from other zombies with malicious intentions to humans who exploit Sakina's condition for their own gain. The interplay between these characters adds depth to the story, highlighting themes of identity, survival, and the blurred line between humanity and monstrosity.

The manga balances its darker elements with moments of humor and absurdity, often using Sakina's predicament to satirize high school life and societal expectations. The artwork complements the tone, with detailed depictions of gore and horror juxtaposed against the mundane settings of school and suburban life. Overall, "Zombie-Bitch SAKINA is in Bitch-girl" offers a unique take on the zombie genre, blending horror and comedy to explore the complexities of its protagonist's undead existence.