In 1892, the Japanese government, military agencies, and private citizens began an informal investigation into a disturbing supernatural phenomenon designated as Uzono Shiniko. According to the core rule of this phenomenon, any entity—whether a human, an animal, or even an inanimate object—that is assigned the name Uzono Shiniko will immediately and inexplicably attract catastrophic disaster. This curse is absolute, transforming a simple water tank into a site of unusual drownings or turning an ordinary object into a weapon of mass misfortune. The story is structured as a collection of investigative files and reports that trace the history of these incidents, but what begins as a clinical, mockumentary-style horror narrative gradually shifts in tone and scope. As the records accumulate, common threads link back to a mysterious place called Uzono from Japan's Heian period, and the world depicted begins to show cracks of underlying wrongness.

The initial phase of the narrative focuses on the chilling, isolated case files of the Uzono Shiniko curse, establishing a world where a single misplaced name can spell doom. Recurring investigators and experts appear across these reports, forming a small cast tasked with understanding and containing the uncontainable. However, approximately a quarter of the way through the overarching narrative, the investigation fails catastrophically. The subtle horror of cursed objects escalates into a full-scale apocalypse. The setting transforms from contemporary Japan into a post-apocalyptic wasteland where the rules of reality have bent. The protagonists, now survivors rather than researchers, must face massive, personified threats that have been corrupted by the Uzono Shiniko name, such as a malevolent living tower or cursed weapons like the Uzono Shiniko Blade, often aided by other cursed entities like the Uzono Shiniko Prostitute.

The narrative arc consequently abandons the slow-burn unease of its initial reports for the desperate pacing of a survival thriller. As the situation spirals out of control, the story delves into the controversial responses of authorities who resorted to extreme measures, including the elimination of citizens, to prevent the curse from spreading, only for these methods to prove monstrous and ultimately futile. The plot follows the remaining survivors as they attempt to weaponize the very curse that destroyed their world, pitting Uzono Shiniko against Uzono Shiniko in a frantic battle for survival. What begins as a series of quiet, unsettling files ends in a climactic, action-driven confrontation where the original clinical tone is replaced by the raw struggle to endure against a world where naming something is the same as destroying it.