"Failure Frame" is a dark fantasy manga series that revolves around a group of students transported to a fantasy world by a goddess who deems them "heroes" destined to save the realm. However, the protagonist, Touka Mimori, is branded as a failure due to his seemingly weak ability, "Poison Resistance," and is exiled to a deadly dungeon. Unlike his classmates, who are celebrated for their powerful skills, Mimori is left to fend for himself in a hostile environment.

The narrative explores Mimori's struggle for survival as he uncovers the true potential of his ability, which is far more lethal than initially perceived. His "Poison Resistance" allows him to manipulate and weaponize toxins, enabling him to defeat powerful monsters and adversaries. As he navigates the dungeon, Mimori encounters other outcasts and forms alliances, gradually gaining strength and resolve. His journey is marked by a growing determination to confront the goddess and the system that discarded him, revealing a deeper conspiracy behind the summoning of the "heroes."

The story delves into themes of betrayal, resilience, and the redefinition of strength. Mimori's character development is central, as he transitions from a marginalized figure to a formidable force challenging the established order. The manga also examines the moral ambiguity of the goddess and the other summoned students, some of whom embrace their roles as heroes while others grapple with the consequences of their newfound powers. The plot is driven by Mimori's quest for vengeance and justice, set against a backdrop of political intrigue and supernatural threats.

"Failure Frame" combines elements of action, survival, and psychological drama, with a focus on the protagonist's transformation and the exploration of a flawed, oppressive world. The series balances intense combat sequences with moments of introspection, creating a narrative that is both gripping and thought-provoking.