"That Wolf-Boy is Mine!" is a supernatural romance manga that centers on Komugi Kusunoki, a high school girl who moves from Tokyo to a rural town to escape the pressures of city life. Struggling to adjust to her new environment, Komugi finds herself drawn to Yuu Ogami, a mysterious and aloof classmate who harbors a secret: he is a wolf spirit in human form. Yuu is one of several animal spirits living among humans, each bound by a curse that prevents them from fully transforming into their animal forms. These spirits include a fox, a rabbit, a tanuki, and a cat, each with distinct personalities and struggles tied to their supernatural identities.

As Komugi becomes more involved with Yuu and the other spirits, she learns about their shared curse and the tragic history that binds them. The spirits were once part of a group that lived freely in the mountains, but a betrayal led to their current predicament. Komugi’s presence begins to disrupt the fragile balance of their lives, as her kindness and determination to understand them challenge their long-held beliefs about humans. Yuu, in particular, grows closer to Komugi, and their relationship evolves from mutual curiosity to a deep emotional connection. However, their bond is tested by the complexities of Yuu’s nature and the lingering effects of the curse.

The narrative explores themes of identity, belonging, and the tension between human and animal instincts. Komugi’s journey is one of self-discovery as she navigates her feelings for Yuu while grappling with the challenges of being an outsider in both the human and spirit worlds. The story balances moments of lighthearted humor and heartfelt emotion with darker undertones, as the characters confront their pasts and the possibility of breaking free from their curses. The interplay between the human and supernatural elements drives the plot forward, creating a compelling blend of romance, mystery, and fantasy.