"The 3page! of three Angels!!" centers on three high school girls—Hikari, Akari, and Yume—who are unexpectedly chosen to become celestial guardians tasked with protecting their town from supernatural threats. Each girl possesses a unique ability tied to their personality: Hikari wields light-based powers, Akari controls fire, and Yume manipulates dreams. Their transformation into "Angels" is triggered by a mysterious artifact discovered in their school, which binds them to their new roles.

The narrative unfolds as the trio balances their ordinary school lives with their newfound responsibilities. They face a series of increasingly dangerous adversaries, including shadowy creatures and rogue entities seeking to disrupt the balance between the human and spiritual realms. The girls must learn to work together, overcoming personal insecurities and conflicts, to harness their powers effectively. Key themes include friendship, self-discovery, and the struggle to maintain normalcy while embracing extraordinary duties.

Supporting characters include their classmate Ren, who becomes an ally and confidant, and a enigmatic mentor figure, Kaito, who provides guidance but harbors secrets about the origins of the Angels' powers. The story explores the girls' growth as individuals and as a team, with each arc delving deeper into the mythology of the Angels and the forces they oppose. The manga blends action, humor, and emotional moments, creating a dynamic and engaging narrative.