Sakura Kawaguchi is a Japanese voice actress from Fukuoka Prefecture, born on June 7. She is affiliated with the talent agency Aoni Production, a connection she established after graduating from the associated voice actor training school, Aoni Juku, in March 2019. Her professional career began in April of that same year, with her debut anime role being various minor characters in the sixth season of GeGeGe no Kitaro.

In the early stages of her career, Kawaguchi has built a diverse portfolio of roles, often voicing supporting characters, children, and townspeople in a wide array of popular long-running and seasonal anime series. Her film work includes roles in major theatrical releases such as Pokémon the Movie: Coco, Suzume, and Dragon Ball Super: Super Hero. She has also lent her voice to characters in video games, including SHOW BY ROCK!! Fes A Live and Kemono Friends 3.

Among her notable anime television roles, she is recognized for playing Haya Kittaka, the operator of Ōji Squad, in the second and third seasons of World Trigger. Her casting in this role was part of a larger announcement of new cast members for the series in 2021. Another significant credit is providing the voice for the character MAMEchi in the short-form anime series JOCHUM, a collaboration between Sanrio and the Japanese idol group JO1, which began airing in 2024.

Kawaguchi's career trajectory shows a consistent pattern of work across different media. She has voiced characters across multiple episodes of franchise anime like Digimon Adventure: and its follow-up Digimon Ghost Game, as well as One Piece and The Fruit of Evolution. Her repertoire also extends to web animations, original video animations, and stage readings. A notable early achievement in her career was receiving the Boista Award at the 4th Kyushu International Voice Actor Contest Seiyu Soul in 2017, which helped launch her professional path.