Simon Prescott is an American voice actor recognized for his extensive work in anime dubs produced in the United States, particularly during the 1980s and 1990s. His career in entertainment began in live-action television and film in 1960, with appearances in series such as Bat Masterson and M Squad, and films like Hell is for Heroes and Hud. He later transitioned to focus primarily on voice acting for animation and video games. Throughout his career, he has also been credited under the names Sy Prescott, Simon Isaacson, and Ben Isaacson.

Prescott's voice acting filmography includes a wide array of roles in English adaptations of Japanese anime. Among his notable parts are Malcolm in the Sanrio fantasy series Yume no Hoshi no Button Nose, also known as Button Nose; Professor Dingy in the comedy series Don-Don Domel to Ron, also known as Wowser; and Dr. Isaac Gilmore in Cyborg 009 The Cyborg Soldier.

He is also known for providing voices in several high-profile anime features and series. These include Dr. Laughton in the film Metropolis, Chief Nakamura in Ghost in the Shell, and Aritomo Yamagata in Rurouni Kenshin. His other anime credits span a broad range of productions, including roles in Akira, Mobile Suit Gundam 0083: Stardust Memory, Outlaw Star, and Samurai Champloo. He was frequently cast in dubs produced by studios such as Streamline Pictures, Animaze, and Saban Entertainment, often appearing alongside a recurring pool of voice actors like Steve Kramer, Wendee Lee, and Michael Sorich.

In addition to animation, Prescott has contributed voices to numerous video games. His work in the medium includes roles in Brave Fencer Musashi, The Bouncer, Ace Combat 5: The Unsung War, and the English-localized versions of the.hack series. His live-action credits later in his career also include voice work in the Power Rangers franchise, where he provided the uncredited voice of Master Vile in Mighty Morphin Power Rangers and Power Rangers Zeo, and voiced Loyax in Power Rangers: Lost Galaxy.