Rie Ishizuka is a Japanese voice actor and actress affiliated with the talent management firm En-kikaku. She was born on April 23, 1964, in Shizuoka Prefecture, Japan, and is a graduate of Tama Art University. Her career in the entertainment industry began in the late 1980s, with her acting debut in the 1988 historical drama "Takeda Shingen," and she has remained active in voice acting for both animation and foreign language dubbing for over three decades.

Ishizuka has built a varied career in anime, taking on roles in a wide range of series. In the 2002 supernatural horror series Demon Lord Dante, she voiced the character Saeko Kodai, who is also the Medusa. Her film work includes providing the voice for Alisa Takakura in the 1999 animated movie Gundress. She also voiced the character Momomi Momoi in the original video animation (OVA) Mezzo Forte. Another notable role was as Ahiru Takamizawa, the secretary to the protagonist, in both the 2004 television series Tetsujin 28 and its 2007 theatrical sequel, Tetsujin 28: Morning Moon of Midday.

Beyond the roles specified, Ishizuka's anime filmography is extensive and demonstrates her range. She has played powerful action-oriented characters like Undine in Claymore and Kai Sanpagita in Air Master, as well as more dramatic roles such as Antonin in Monster and Sayoko in Shangri-La. She has also appeared in long-running and popular series, with a guest role as Yoko Sawaki in Case Closed (Detective Conan) and as the younger version of the character Tetsuo Kaga in Hikaru no Go. Her career has continued into the modern era with roles such as the voice of Longclaw, the owl guardian, in the live-action/CGI films Sonic the Hedgehog and Sonic the Hedgehog 2.

A significant portion of Ishizuka's career is dedicated to Japanese dubbing (fukikae) of live-action foreign films and television series. She has been the regular Japanese voice for several prominent Western actors, including Kirsten Dunst in her early roles, Thandie Newton, and Katherine Heigl. Her dubbing credits are prolific and include starring roles in major Hollywood films such as Mission: Impossible II (as Nyah Nordoff-Hall), The Mummy and The Mummy Returns (as Evelyn Carnahan), and the American Pie films (as Vicky Lathum). On television, she has provided the Japanese voice for Izzie Stephens in Grey's Anatomy, Sabrina Spellman in Sabrina the Teenage Witch, and Teyla Emmagan in Stargate Atlantis. This body of dubbing work forms a core part of her professional legacy.