"Akubi Girl" centers around a young girl named Akubi, a mischievous and energetic demon who emerges from a magical mirror. Akubi is summoned by a boy named Sawaki, who accidentally breaks the mirror while cleaning his house. Upon her arrival, Akubi explains that she is bound to grant Sawaki three wishes as part of her summoning ritual. However, her interpretations of these wishes often lead to chaotic and humorous outcomes, as she tends to twist the intent of Sawaki's desires for her own amusement.

The series unfolds through episodic adventures, with each episode focusing on Sawaki's attempts to navigate the unpredictable consequences of his wishes. Akubi's playful and often selfish nature complicates matters, as she frequently prioritizes her own entertainment over Sawaki's well-being. Despite her antics, a peculiar bond forms between the two, blending moments of camaraderie with constant bickering.

Supporting characters include Akubi's rival, Akubi-chan, a more refined and disciplined demon who occasionally interferes with Akubi's schemes. Additionally, Sawaki's classmates and family members occasionally become entangled in the chaos, further expanding the comedic scope of the series. The narrative thrives on its lighthearted tone, blending supernatural elements with slapstick humor and situational comedy.

Themes of friendship, responsibility, and the unintended consequences of one's actions are subtly woven into the story, though the primary focus remains on the comedic interactions between Akubi and Sawaki. The series maintains a straightforward, episodic structure, with each installment offering a self-contained story while contributing to the evolving dynamic between the main characters.