"Gakkō no Kowai Uwasa: Hanako-san ga Kita!!" is a horror anime series centered around the urban legend of Hanako-san, a ghost said to haunt school bathrooms. The story unfolds in a high school setting, where students begin to experience strange and terrifying occurrences linked to the legend. The narrative explores the lives of several students who encounter Hanako-san, each episode delving into their personal fears, secrets, and the consequences of their actions.

The series introduces a diverse cast of characters, each with their own connection to the supernatural events. Among them is Nene Yashiro, a curious and brave student who becomes deeply involved in the mystery after a personal encounter with Hanako-san. Other key characters include Kou Minamoto, a transfer student with a family background in exorcism, and Aoi Akane, a popular student whose life takes a dark turn due to her involvement with the legend.

As the story progresses, the students uncover the truth behind Hanako-san's existence and the reasons for her haunting. The plot intertwines their personal struggles with the overarching mystery, revealing how their choices and emotions influence the supernatural phenomena. The series balances moments of tension and horror with character-driven drama, exploring themes of guilt, redemption, and the impact of rumors and fear on human behavior.

The narrative structure is episodic, with each episode focusing on a different student or aspect of the legend, while maintaining a cohesive storyline that builds toward a climactic resolution. The series effectively uses the school setting to create an atmosphere of unease, blending everyday school life with supernatural elements to heighten the sense of dread. Through its exploration of the Hanako-san legend, the series offers a compelling mix of horror and emotional depth, making it a notable entry in the genre.