"My Pico" is a short anime series that centers around the relationship between two main characters, Pico and Tamotsu. Pico is a young, androgynous boy who works at a café owned by his older brother, Chico. Tamotsu, a regular customer at the café, becomes intrigued by Pico's appearance and demeanor. The narrative explores their evolving relationship, which begins with Tamotsu's curiosity and gradually develops into a more intimate connection. The story unfolds in a slice-of-life setting, with the café serving as a central location where much of the interaction between the characters takes place.

The series delves into themes of identity, attraction, and the complexities of human relationships. Pico's androgynous appearance and youthful innocence play a significant role in shaping the dynamics between him and Tamotsu. Tamotsu, on the other hand, is portrayed as an older, more experienced individual who is drawn to Pico's unique charm. Their interactions are marked by a mix of tenderness and tension, as they navigate their feelings for each other.

The plot progresses through a series of encounters that highlight the growing bond between Pico and Tamotsu. These moments are interspersed with scenes that provide insight into their individual lives and personalities. The series maintains a focus on the emotional and psychological aspects of their relationship, rather than relying heavily on external conflicts or dramatic events.

Supporting characters, such as Chico, add depth to the narrative by offering different perspectives on the main characters' relationship. Chico's protective nature towards Pico introduces an element of familial concern, which contrasts with Tamotsu's more personal and romantic interest in Pico.

Overall, "My Pico" presents a straightforward yet nuanced exploration of the connection between its two central characters, set against the backdrop of a quiet, everyday environment. The series emphasizes the subtleties of their interactions and the gradual development of their relationship, making it a character-driven narrative that prioritizes emotional depth over plot complexity.