Shōko Ieiri functions as Tokyo Jujutsu High's primary physician, wielding the rare Reverse Cursed Technique to heal others. This power enables regeneration of lost limbs and treatment of severe injuries, establishing her as medically indispensable. Her expertise extends to conducting autopsies and providing critical biological insights, such as identifying Mahito's human-transfiguration ability and theorizing the Culling Game's fatal technique-removal mechanism. Born November 7, 1989, she enrolled at Tokyo Jujutsu High in 2005 alongside Satoru Gojo and Suguru Geto. As a student, she sported short hair with left-swept bangs and the standard uniform, maintaining a casual demeanor. She often smoked openly despite her youth and avoided involvement in Gojo and Geto's philosophical disputes. Her adult appearance features long brown hair typically tied in a ponytail while working, a mole under her right eye, and persistent dark circles. She wears a white lab coat over a blue turtleneck, navy pants, and cream heels. Her personality balances nonchalance and emotional detachment, blending laid-back attitudes with professional stoicism. She smokes habitually, having quit for five years before resuming during high-stress events like the Shibuya Incident, citing nostalgia for her school days. She dislikes sweets but consumes alcohol heavily, attributing this to night shift stress. Though generally apolitical, she aligns with Gojo due to their longstanding friendship. After graduation, she obtained a medical license in two years by falsifying exam eligibility documents. During school years, she assisted Gojo in testing his Infinity technique and witnessed his advancement in Reverse Cursed Technique. Following Geto's defection, she confronted him in Shinjuku, calmly questioning his motives before notifying Gojo of his location. As an adult, she prioritizes medical duties over emotional involvement, exemplified by insisting on autopsying Yuji Itadori despite Gojo's distress. She also withheld Yuji's revival from higher authorities at Gojo's request. In major conflicts, she established field hospitals, notably during the Shibuya Incident where she healed critically injured personnel like Kiyotaka Ijichi and Takuma Ino. Later, she aided in unsealing Gojo by treating Hana Kurusu's injuries and explained Reverse Cursed Technique principles to optimize Yuji Itadori and Choso's healing abilities. After Gojo's death, she prepared his corpse for Yuta Okkotsu's attempted brain-transfer technique and oversaw Tsumiki Fushiguro's funeral arrangements. During this period, she discarded her cigarettes, signaling another attempt to quit smoking. In "Gekijōban Sōshūhen Juju Sanpo," a lighthearted mini-anime set during her school years, she appears alongside Gojo and Geto in comedic, non-canon scenarios. This portrayal emphasizes her more relaxed interactions with classmates before her medical career responsibilities.