Ruri serves as the priestess of Ishigami Village, elder daughter to Chief Kokuyo and sister to Kohaku. Her long blonde hair, blue-green eyes, and features reflect mixed Japanese and American descent as a descendant of astronaut Lillian Weinberg. She typically wears a primitive blue ankle-length sundress with a left-leg split secured by clasps and a rope necklace bearing the village's star symbol, later adopting contemporary dresses after modern clothing's introduction. Gentle, kind, and noble, Ruri balances her priestess duties with an underlying assertiveness. She prioritizes tradition over personal desire, accepting marriage to the Grand Bout winner. Her formidable willpower sustained her through years of severe pneumonia, aided by Kohaku. She exhibits deep concern for her sister's safety, noticing subtle changes like altered hairstyles. After recovering, she displays energetic, tomboyish traits, sprinting freely. Her abilities include perfect retention of the Hundred Tales, acute observational skills noting interpersonal dynamics and physical changes, and commanding authority during village crises. She shares Kohaku's physical strength, lifting and throwing her effortlessly. Confined by illness, she mastered handicrafts like sewing needle creation and battery production assistance. Romantic moments elude her, marked by an immediate divorce from Senku after their forced marriage and Chrome's repeated failure to acknowledge her interest. Born to the village chief roughly eighteen years before Senku's arrival, Ruri heard the Hundred Tales as childhood lullabies. At twelve, she contracted pneumonia, receiving a poor prognosis. Chrome vowed to find a cure while Kohaku carried hot spring water to ease her symptoms. At fourteen, she inherited responsibility for memorizing the Hundred Tales from her mother, who died when Ruri was fifteen. During the Village Games Arc, Ruri collapses upon recognizing Senku's surname. After he accidentally wins the Grand Bout, she reluctantly agrees to marry him per tradition, but he divorhes her immediately to prioritize pneumonia medication. She volunteers as the first subject for Senku's antibiotics despite risks. Her condition temporarily worsens due to bacterial resistance before recovery, leading to emotional reunions with Kohaku and Kokuyo. In the Village Origins Arc, post-recovery, Ruri reveals the village's founding by Byakuya Ishigami and fellow astronauts. She discloses Senku's full name and legacy within the Hundred Tales, explaining the village's name. She guides Senku to Byakuya's grave marker and conveys his final message. During the Communications Arc, Ruri assists in battery production for the stone world's first cellphone. Testing it with Chrome, she shares a tale about bees communicating with the dead, inadvertently helping Senku realize Byakuya left a recorded message. She later listens to Lillian Weinberg's recording on the constructed record player. In the Age of Exploration Arc, Ruri witnesses cotton candy creation and admires jewels from cave expeditions. She nearly confesses to Chrome via new communication technology, interrupted by an external signal. Their relationship culminates in Chrome's proposal and marriage, depicted in the spin-off "Dr. Stone: 4D Science."