Shoko Ieiri is the primary medical doctor at Tokyo Jujutsu High, utilizing her rare reverse cursed technique to heal others. This vital skill allows her to regenerate lost limbs and save sorcerers from near-fatal conditions, as seen when she treated Nanami Kento after his fight with Mahito and stabilized Kiyotaka Ijichi and Atsuya Ino during the Shibuya Incident. Her expertise combines standard medical knowledge with specialized cursed energy application for regeneration and injury treatment.
Physically, she is a tall woman with long brown hair, typically tied in a ponytail at work, and exhibits dark circles under her eyes. A distinguishing mole sits beneath her right eye. Her standard attire includes a white lab coat over a blue turtleneck sweater, navy pants, and cream-colored high-heeled shoes. As a student, she wore the Jujutsu High uniform with short hair and lacked her adult tiredness.
Her personality blends stoicism with dry wit. She maintains a consistently calm and nonchalant demeanor, even during events like Suguru Geto's defection or the Shibuya Incident. This detachment enables efficient task prioritization, such as insisting on autopsies over emotional reactions when Yuji Itadori initially "died." Despite her reserved exterior, she demonstrates loyalty through actions like discreetly supporting Satoru Gojo's plans for Yuji and offering emotional reassurance to guilt-ridden students. She copes with job stress through smoking—a habit resumed after five years quit—and prefers alcohol over sweets.
Her background includes being classmates with Satoru Gojo and Suguru Geto during their second year at Jujutsu High. Though not combat-focused, she participated in missions alongside them. After graduation, she obtained a medical license within two years by fabricating exam eligibility credentials and became Tokyo Jujutsu High's resident physician. She shared candid banter with Gojo and Geto, often teasing them as "idiots" while valuing their bond. After Geto's descent into villainy, she remained pragmatically composed during encounters but immediately alerted Gojo to his presence.
Her abilities center exclusively on externally applying reverse cursed technique to heal others—a skill even Gojo cannot replicate, though she struggles to articulate its mechanics for teaching. Her medical acumen led to critical discoveries: identifying Mahito's transfigured humans as altered humans and theorizing the Culling Game's technique-removal penalty causes fatal brain damage. During large-scale conflicts like Shibuya and Shinjuku, she operates triage stations to treat wounded sorcerers under ally protection.
She interacts through drinking with colleagues like Ijichi and Gojo, shares a mutual dislike of sweets with Utahime Iori, and mentors students including Megumi Fushiguro and Nobara Kugisaki. While not politically aligned with Jujutsu High's administration, she sides with Gojo due to personal closeness. She dismisses romantic notions toward him or Geto, emphasizing platonic bonds.