Chizuru Yukimura, a young woman journeying to Kyoto in the Bakumatsu era, seeks her missing father, Kodo Yukimura—a physician pioneering Western medicine. Unknowingly stepping into his shadowy legacy involving the Water of Life, an elixir spawning Furies (immortal beings with enhanced prowess and violent impulses), she is rescued from an ambush by the Shinsengumi. Mistaken for a boy in her disguise, her true identity as Kodo’s daughter compels the group to shelter her, intertwining her fate with their investigation into his experiments. Her bloodline conceals demonic ancestry, a legacy entwined with her family’s past. Kodo’s research sought to forge a Fury army to usurp humanity, exploiting Chizuru’s hybrid heritage to produce offspring merging both lineages. This truth pits her against her father’s ethically fraught ambitions and her brother Kaoru’s efforts to sway her to their side. She resolutely opposes their schemes, anchoring herself to the Shinsengumi’s principles. Amid clashes like Toba-Fushimi and the retreat to Aizu, Chizuru stands unflinching beside the Shinsengumi, notably Vice Commander Toshizo Hijikata. As comrades fall to the elixir’s corruption or battlefield deaths, her resilience shines through captivity, perilous journeys, and the use of her blood’s curative power to stabilize Hijikata following near-fatal wounds. Her bond with Hijikata deepens from pragmatic alliance to heartfelt devotion, sealed by reciprocal confessions of love. Amid surrounding turmoil, her compassion persists, anchoring those struggling with their humanity amid Fury transformations. Though Kodo’s designs are foiled, the Shinsengumi’s heavy toll lingers. Chizuru’s arc traces her transformation from a determined yet untested seeker into a linchpin of the conflict, reconciling demonic inheritance with human compassion. Choices driven by safeguarding others—even at personal cost or when confronting her lineage’s darkness—define her journey.