Misato appears as a supporting character across various Mazinger narratives. She is a distant relative of Boss, with her role being relatively minor in the anime adaptation but more prominent in Gosaku Ōta's manga, where she meets a tragic end. Her appearance differs between media: the manga shows her with long straight blonde hair, typically in a short-sleeved shirt and skirt, while the anime depicts wavy brown hair, a green sweater, and blue pants.

Characterized as friendly and polite, she exhibits resilience and capability during crises such as attacks by the Iron Masks or convicts. Her presence sometimes sparks interpersonal tension, particularly with Sayaka Yumi over attention from Koji Kabuto, though they eventually form a friendship.

Professionally, she serves first as a housekeeper for the Kabuto household and later for the Photon Power Laboratory, excelling in domestic tasks like cooking and cleaning. Beyond housekeeping, she demonstrates proficiency with firearms, skill in helicopter piloting, and a background in electronics, enabling her to repair laboratory equipment such as radar systems. These abilities lead Professor Yumi to formally recruit her into the laboratory staff.

Key events define her arc: during an assault on the Kabuto residence, she ensures Shiro Kabuto's safety. Her actions in that crisis—disarming attackers and piloting a VTOL to neutralize threats—cement her value to the Photon Power team. She routinely performs chores at the laboratory while interacting with pilots and staff. In one incident, she breaks Koji Kabuto's mind trance by knocking him against a rock during a Mechanical Beast confrontation.

Her story concludes during Great Mazinger events when government forces target the laboratory. While aiding the staff's escape, she detects a pursuer and attempts an attack but is killed by Marquis Janus. Her death is mourned by the laboratory community.