In a fantasy world where magic is taught at academies, Pluto is a sixteen-year-old girl recognized as a genius mage. Rather than taking up a post defending the realm, she spends her days devouring every book in the library, driven by an insatiable thirst for knowledge. When a librarian grants her access to a sealed collection of forbidden texts, Pluto discovers a volume that sparks a singular obsession: she wants to become a seedbed for exotic creatures of every species. Calculating and methodical, she enchants her own body to grant herself immortality and physical resilience, then sets out alone on a journey to fulfill that desire.

The story follows Pluto as she travels through untamed wilderness, seeking out monsters and magical beings to mate with. Her first stop is a marshland where she encounters a Roper, a tentacled plant-like organism. She willingly submits to it, becomes pregnant, and after a gestation period gives birth to a large number of offspring. Those new creatures inherit her magical potency and grow stronger than typical Ropers, eventually spilling into nearby territories and causing unintended ecological disruption. This pattern repeats as Pluto continues her travels: in the Nyx Forest, she is attacked by a giant insectoid Hornet, and she again uses her immortal body to survive and propagate.

Along the way, Pluto is confronted by Pandora, a brown-skinned female knight who was her underclassman at the academy. Pandora appears determined to bring Pluto back home, leading to a clash between Pluto's unorthodox personal mission and the expectations of the society she left behind. The narrative interweaves these confrontations with Pluto's ongoing encounters with new species, each encounter deepening the consequences of her choices for both herself and the world around her.

The setting is a medieval fantasy realm with established magical academies, human kingdoms, and untamed monster habitats. Pluto herself is the central and almost sole point of view character: brilliant, curious, and utterly amoral in her pursuit of experience. Her immortality removes any physical cost from her actions, leaving only the social and environmental fallout as sources of conflict. The story combines explicit adult content with a darkly comedic tone, as Pluto's cheerful scientific approach to cross-species reproduction treats each encounter as another experiment in a boundless field of study. Ongoing at two collected volumes and multiple serialized chapters, the series continues to expand Pluto's bestiary and the repercussions of her journey.