"Sexy & Dangerous Teachers" is a manga series that revolves around the lives of a group of unconventional educators working at a high school. The narrative centers on their dual roles as both mentors and protectors, blending elements of comedy, drama, and action. The teachers, each with distinct personalities and backgrounds, are tasked with guiding their students through academic challenges while also shielding them from external threats, including gang violence, bullying, and societal pressures.

The protagonist, a charismatic and enigmatic teacher, often takes the lead in resolving conflicts, employing unorthodox methods that blur the lines between discipline and mentorship. Other key characters include a former delinquent turned educator, whose past experiences inform their approach to teaching, and a sharp-witted female teacher who balances her no-nonsense attitude with a deep care for her students. Together, they form a dynamic team that navigates the complexities of their profession while addressing the personal struggles of their pupils.

The plot unfolds through a series of episodic arcs, each focusing on specific students or challenges faced by the school. Themes of redemption, personal growth, and the transformative power of education are recurrent, as the teachers often go beyond their duties to inspire and protect their charges. The series also explores the teachers' own vulnerabilities and backstories, adding depth to their characters and highlighting the human side of their profession.

Interpersonal relationships, both among the faculty and between teachers and students, play a significant role in the narrative. The interactions are often laced with humor and heartfelt moments, creating a balance between the series' lighter and more serious tones. While the teachers' methods may be unconventional, their dedication to their students' well-being remains a central theme throughout the story.