"Prunus Girl" is a romantic comedy manga that explores themes of gender identity and relationships through its central characters, Aikawa and Maki. Aikawa, the protagonist, is a high school student who meets Maki, a classmate with an androgynous appearance. Maki’s gender is intentionally left ambiguous throughout the series, often blurring the lines between male and female, which becomes a recurring point of intrigue and humor. Aikawa is initially confused by Maki’s playful teasing and ambiguous behavior but gradually develops a close bond with them.

The narrative revolves around the evolving relationship between Aikawa and Maki, as well as their interactions with classmates and friends. Maki frequently challenges societal norms and expectations regarding gender, often using humor and wit to navigate situations. Aikawa, while initially hesitant, becomes increasingly accepting and supportive of Maki’s unique identity. The story balances lighthearted comedic moments with more introspective scenes, exploring themes of self-expression, acceptance, and the fluidity of identity.

Supporting characters, such as Aikawa’s childhood friend Kizuna and other classmates, add depth to the story by providing different perspectives on Maki’s identity and the dynamics of their relationships. The manga avoids definitive conclusions about Maki’s gender, instead focusing on the emotional connections and personal growth of the characters. Through its blend of humor, romance, and thoughtful exploration of gender, "Prunus Girl" presents a narrative that is both entertaining and thought-provoking.