"My Pathetic Vampire Life" centers on the life of a vampire named Myucel Foaran, who struggles with the mundane and often comedic challenges of modern existence. Unlike traditional depictions of vampires as powerful and fearsome creatures, Myucel is portrayed as weak, socially awkward, and perpetually unlucky. His inability to adapt to human society and his lack of typical vampiric abilities make him an outlier among his kind.

The narrative explores Myucel's daily life as he navigates a world where humans and supernatural beings coexist. Despite his vampiric nature, he is unable to perform basic tasks expected of his species, such as transforming into a bat or hypnotizing humans. His struggles are compounded by his low social status among other vampires, who view him as a failure. Myucel's interactions with humans are equally fraught, as he often finds himself in embarrassing or absurd situations due to his incompetence.

Key characters include Myucel's human friend, a high school girl named Akari, who often helps him despite his constant blunders. Akari's pragmatic and no-nonsense attitude contrasts sharply with Myucel's ineptitude, creating a dynamic that drives much of the series' humor. Another significant character is a fellow vampire named Serara, who, unlike Myucel, embodies the traditional traits of a vampire but occasionally assists him out of pity or obligation.

The plot unfolds through episodic chapters, each highlighting Myucel's misadventures as he attempts to fit into a world that seems to conspire against him. Themes of identity, belonging, and the struggle to find one's place in society are subtly woven into the comedic framework. The series balances humor with moments of introspection, offering a nuanced portrayal of a character who defies conventional vampire tropes. Through its blend of comedy and character-driven storytelling, "My Pathetic Vampire Life" presents a unique take on the vampire genre, focusing on the struggles of an underdog in a world that expects greatness.