"World Destruction: Futari no Tenshi" is a manga series that expands on the narrative of the "World Destruction" franchise, originally conceived as a multimedia project. The story is set in a world where humans and beastmen coexist, though tensions between the two races are high. The central conflict revolves around the World Destruction Committee, a group dedicated to annihilating the world, and the World Salvation Committee, which seeks to prevent this catastrophe.

The protagonist, Kyrie Irunisu, is a young man with a mysterious past and a unique ability to wield the power of destruction. He is accompanied by Morte Ashera, a beastman girl who is a member of the World Salvation Committee. Morte is determined to stop the World Destruction Committee and protect the world, but her motivations are deeply personal, tied to her own tragic history. Together, Kyrie and Morte form an unlikely alliance, their contrasting goals and personalities creating a dynamic partnership.

As the story progresses, Kyrie and Morte encounter various allies and adversaries, each with their own stakes in the world's fate. Among them is Toppi, a cunning and resourceful thief who joins their journey, adding a layer of humor and unpredictability to the group. The narrative explores themes of identity, morality, and the consequences of power, as the characters grapple with their roles in the impending destruction or salvation of their world.

The plot is driven by the characters' quest to uncover the truth behind the World Destruction Committee's plans and the origins of Kyrie's destructive abilities. Along the way, they face numerous challenges, including battles with powerful enemies, moral dilemmas, and revelations about their own pasts. The story balances action-packed sequences with moments of introspection, delving into the emotional and psychological struggles of its characters.

"World Destruction: Futari no Tenshi" is a tale of conflict and camaraderie, set against the backdrop of a world teetering on the brink of annihilation. The manga explores the complexities of its characters and their intertwined destinies, offering a narrative that is both engaging and thought-provoking.