"So I Can't Play H!" is a manga series that blends elements of comedy, romance, and supernatural themes. The story centers around Ryosuke Kaga, a high school student who has lived a life of misfortune, particularly in his interactions with women. After a series of embarrassing incidents, Ryosuke becomes convinced that he is cursed to never succeed in romantic or sexual pursuits. His life takes a dramatic turn when he encounters Lisara Restall, a demon girl who claims to be his servant. Lisara explains that Ryosuke has inherited a contract with her family, binding her to serve him. However, the contract comes with a catch: Ryosuke must remain a virgin, as losing his virginity would nullify the pact and potentially endanger his life.

As Ryosuke navigates his new reality, he is introduced to a world filled with supernatural beings, including other demons, angels, and spirits. Lisara, despite her role as his servant, often clashes with Ryosuke due to her fiery and independent personality. Their relationship evolves into a mix of comedic tension and budding romance, complicated by the restrictions of the contract. Alongside Lisara, Ryosuke encounters other key characters, such as Sherington, a demon butler who oversees the contract, and Elsa, an angel who becomes involved in Ryosuke's life, adding further complexity to his situation.

The narrative explores Ryosuke's attempts to balance his desire for a normal romantic life with the constraints imposed by the supernatural contract. The series frequently employs humor, often derived from Ryosuke's awkwardness and the absurdity of his predicament, while also delving into themes of trust, loyalty, and self-discovery. As the story progresses, Ryosuke and Lisara face various challenges, including rival demons, misunderstandings, and the ever-present threat of the contract's conditions. The interplay between the characters and their evolving relationships drives the plot forward, creating a mix of lighthearted moments and deeper emotional undertones.