Isabella Simi is a Brazilian actress, voice actress, and singer known for her work in the dubbing of animated series and films for the Brazilian Portuguese market. Her professional activities are centered in Brazil, where she lends her voice to characters in a variety of international productions, including a significant number of anime series.

Simi has voiced several notable anime characters. In the series Drifting Dragons, she is the voice of Takita, the rookie crew member of the draking ship Quin Zaza. She voices the elf Halkara in the fantasy comedy I've Been Killing Slimes for 300 Years and Maxed Out My Level, a role she has reprised for the series' second season. In the romantic comedy Rent-A-Girlfriend, Simi provides the voice for Mami Nanami, the protagonist's manipulative ex-girlfriend. Her other prominent anime roles include Ryuji Ayukawa in the art-themed drama Blue Period and Saki Hanakago in the supernatural thriller Platinum End. She also voices Tsukasa Tsukuyomi, one of the two main characters in the romantic comedy TONIKAWA: Over The Moon For You.

Beyond the roles listed, Simi's career encompasses a broad range of other characters. She is well-known for voicing Megumin in the popular isekai comedy KONOSUBA – God's Blessing on this Wonderful World!. Her portfolio also includes Aries in Fairy Tail, Charmy Pappitson in Black Clover, Ichigo in DARLING in the FRANXX, and Theresia Van Astrea in Re:Zero. In addition to anime, her voice work extends to animated series like Steven Universe, where she voices Blue Pearl, and Miraculous: Tales of Ladybug & Cat Noir, as Alix Kubdel. She is also the Brazilian Portuguese voice for characters in live-action productions, such as Samantha LaRusso in Cobra Kai and the title character in the film Alita: Battle Angel.

A recurring aspect of Simi's professional career is her collaboration with specific dubbing studios and directors. Much of her work on anime series, including Rent-A-Girlfriend, Platinum End, and I've Been Killing Slimes for 300 Years, has been produced by Som de Vera Cruz Estúdios. She frequently works under the direction of Erick Bougleux and Leonardo Santhos, who have directed the dubbing for several of these projects.