"Eyedrops" is a short-form anime series that revolves around a unique and surreal premise centered on the concept of eye drops and their bizarre effects on the characters. The story unfolds in a world where a mysterious brand of eye drops, known as "Eyedrops," grants users the ability to see strange and fantastical visions. These visions range from whimsical and humorous to unsettling and surreal, often blurring the line between reality and imagination.

The protagonist, a young man named Aoi, stumbles upon the Eyedrops and begins using them out of curiosity. Each episode explores the consequences of his experimentation with the drops, as well as the experiences of other characters who encounter them. The eye drops act as a catalyst for bizarre and unpredictable events, transforming mundane situations into extraordinary and often absurd scenarios. The narrative is episodic, with each installment presenting a self-contained story tied together by the recurring theme of the eye drops' effects.

Aoi is joined by a small cast of characters, including his friend Miki, who becomes entangled in the strange occurrences brought on by the eye drops. Other characters, such as a mysterious salesman who distributes the drops and various individuals who cross paths with Aoi, contribute to the series' exploration of its central concept. The interactions between these characters are often driven by the surreal and unpredictable nature of the eye drops, creating a blend of comedy, fantasy, and occasional moments of introspection.

The plot does not follow a traditional linear structure but instead focuses on the episodic exploration of the eye drops' effects. Each episode introduces new scenarios, ranging from Aoi seeing fantastical creatures in his everyday surroundings to characters experiencing exaggerated emotional states or bizarre transformations. The series maintains a lighthearted and comedic tone, though it occasionally delves into more abstract and thought-provoking territory, reflecting on themes of perception, reality, and the consequences of altering one's vision of the world.

"Eyedrops" is characterized by its imaginative and unconventional storytelling, using the eye drops as a narrative device to explore a wide range of creative and surreal ideas. The series' brevity and episodic format allow for quick, engaging stories that highlight the unpredictable and often humorous consequences of the eye drops' influence on the characters' lives.