"Gakuen Saimin Reido" is an anime series set in a high school where a mysterious phenomenon begins to affect the students and faculty. The story centers around a group of individuals who find themselves entangled in a series of events triggered by the sudden appearance of a hypnotic force. This force causes those exposed to it to fall into a trance-like state, leading to a loss of control over their actions and decisions. The narrative explores the consequences of this phenomenon as it spreads throughout the school, creating chaos and disrupting the normal order.

The main characters include a male student who becomes one of the first to notice the strange occurrences. He is joined by a female classmate who also becomes aware of the hypnotic influence and seeks to uncover its source. Together, they attempt to understand the nature of the phenomenon and its origins, while also trying to protect themselves and others from its effects. As the story progresses, additional characters are introduced, each with their own reactions to the situation, ranging from resistance to submission.

The plot delves into themes of control, manipulation, and the fragility of human willpower. The hypnotic force serves as a catalyst for exploring how individuals respond when their autonomy is compromised. The series examines the psychological and social dynamics that emerge as the characters navigate the increasingly unstable environment of their school. Relationships are tested, alliances are formed, and the boundaries between reality and illusion become blurred.

As the characters work to unravel the mystery, they encounter various obstacles, including those who seek to exploit the hypnotic force for their own purposes. The narrative builds tension as the stakes rise, with the potential for the phenomenon to extend beyond the school and affect the wider world. The series concludes with a resolution that ties together the central mystery while leaving room for interpretation regarding the long-term implications of the events that transpired.