"My New Boss Is Goofy" centers around Momose, a young office worker who has recently transferred to a new company after enduring a toxic work environment at his previous job. Haunted by memories of his overbearing and abusive former boss, Momose approaches his new workplace with trepidation, fearing a repeat of past experiences. However, his anxieties are quickly challenged when he meets his new boss, Shirosaki, a cheerful and eccentric man whose carefree demeanor contrasts sharply with Momose's expectations.

Shirosaki is depicted as a kind-hearted and somewhat clumsy individual, often engaging in humorous antics that baffle his subordinates. Despite his goofy behavior, he is deeply supportive of his team, fostering a positive and inclusive work environment. As Momose interacts with Shirosaki and his colleagues, he begins to shed his apprehensions and gradually adapts to the new workplace culture. The series explores themes of personal growth, workplace dynamics, and the importance of supportive leadership, all while maintaining a lighthearted and comedic tone.

The narrative unfolds through episodic vignettes, each highlighting the quirky interactions between Momose, Shirosaki, and their coworkers. These episodes often blend humor with moments of genuine warmth, showcasing the evolving relationships within the office. Secondary characters, such as the diligent and serious Hakutou and the easygoing yet perceptive Kurosaki, add depth to the story, contributing to the ensemble dynamic that drives the series forward.

Through its portrayal of a workplace that prioritizes camaraderie and mutual respect, "My New Boss Is Goofy" offers a refreshing take on office life, emphasizing the transformative power of a positive environment. The series balances comedy with subtle emotional undertones, creating a narrative that resonates with viewers familiar with the challenges of navigating professional relationships.