"Neo Yokio: Pink Christmas" is a holiday-themed anime special that expands on the world of the original "Neo Yokio" series. Set in the fictional metropolis of Neo Yokio, a city blending futuristic technology with old-world aristocracy, the story revolves around Kaz Kaan, a fashionable demon slayer and socialite. Kaz is tasked with investigating a series of mysterious events during the Christmas season, which threaten to disrupt the city's festive atmosphere.

The narrative begins with Kaz enjoying the holiday season alongside his friends and rivals, including his robotic butler Charles, his ex-girlfriend Helena, and his rival Arcangelo. However, the festivities take a dark turn when a malevolent force begins targeting the city's elite, turning them into grotesque, pink-colored monsters. Kaz, with his signature blend of vanity and reluctant heroism, must uncover the source of this supernatural threat.

As the investigation unfolds, Kaz discovers that the disturbances are linked to a cursed pink ornament, which embodies the materialistic and superficial tendencies of Neo Yokio's high society. The ornament's influence spreads chaos, forcing Kaz to confront not only the external threat but also his own insecurities and the shallow values of the world he inhabits. Along the way, he receives assistance from his loyal butler Charles and encounters unexpected allies, including Lexy, a journalist determined to expose the truth behind the ornament's curse.

The story culminates in a climactic battle against the ornament's malevolent power, during which Kaz must rely on his wit, charm, and demon-slaying skills to save Neo Yokio. The resolution highlights themes of self-reflection and the importance of genuine human connections over material wealth, while maintaining the series' signature blend of satire and absurdity. The special retains the original series' distinctive aesthetic, combining vibrant visuals with a quirky, offbeat tone, and further explores the eccentricities of its characters and setting.