"Nōgyō Musume!" centers on Ichigo Matsushima, a high school girl who moves from Tokyo to the countryside to live with her grandmother after her parents relocate overseas. The series explores her adjustment to rural life, particularly the challenges of farming, which is entirely new to her. Ichigo’s grandmother, Akane Matsushima, is a seasoned farmer who runs a small agricultural business, and she becomes Ichigo’s primary guide in learning the intricacies of farming.

The narrative unfolds through Ichigo’s daily experiences as she navigates the demands of agricultural work, from planting crops to tending livestock. Her initial struggles with the physical labor and unfamiliar routines are contrasted with her growing appreciation for the simplicity and rewards of farm life. Alongside her grandmother, Ichigo interacts with other local characters, including fellow farmers and classmates, who provide both support and occasional comedic relief. These interactions highlight the close-knit nature of rural communities and the importance of cooperation in agricultural work.

As the series progresses, Ichigo begins to develop a deeper connection to the land and the lifestyle. She learns about sustainable farming practices, the seasonal cycles of agriculture, and the value of hard work. The story also touches on themes of perseverance, adaptation, and the generational transfer of knowledge, as Ichigo gradually becomes more skilled and confident in her abilities. The series balances lighthearted moments with educational insights into farming, making it both entertaining and informative.

The characters are grounded and relatable, with Ichigo’s growth serving as the central focus. Her grandmother, Akane, is portrayed as a wise and patient mentor, embodying the traditional values of rural life. The supporting cast, including Ichigo’s classmates and neighbors, add depth to the narrative by showcasing diverse perspectives on farming and rural living. Through its episodic structure, "Nōgyō Musume!" offers a slice-of-life portrayal of agricultural life, emphasizing the joys and challenges of working the land while fostering a sense of community and resilience.