Yuzuriha Ogawa debuted as a modern Japanese high school student moments before a global petrification event froze humanity in stone for roughly 3,700 years, interrupting Taiju Oki's confession. Revived during the Vs. Tsukasa Arc using Senku Ishigami and Taiju's nitric acid-based fluid, she immediately faced Tsukasa Shishio's threat to her life to force Senku to reveal the revival secret. Tsukasa cut her long hair short to intimidate Senku. Following Senku's staged death, Yuzuriha and Taiju infiltrated the Tsukasa Empire as spies for the Kingdom of Science. Yuzuriha employed her exceptional tailoring skills to painstakingly reassemble petrified humans shattered by Tsukasa, using primitive adhesives. This vital reconstruction continued into the Communications Arc, where she also helped persuade defectors like Nikki Hanada and Ukyo Saionji to join Senku's cause, later aided by Yo Uei seeking redemption. Inspired by Gen Asagiri during the Age of Exploration Arc, Yuzuriha spearheaded textile recreation, establishing a clothing store. She crafted garments for both revived modern humans and Ishigami villagers, supplied materials for scientific projects like hot air balloons, and collaborated with Kaseki on a model globe. She managed farming fields and participated in Gen's incentive programs, recognizing their manipulative nature. Taiju later won one of her hats as a farming prize. Sailing on the Perseus during the Treasure Island Arc, Yuzuriha applied knowledge from Senku's scientific lectures. After petrification by Kirisame, she was revived and repaired shattered statues alongside Soyuz. She witnessed the development of non-lethal weapons and critically exposed the Petrification Kingdom's leader by reconstructing his statue. Petrified again by Ibara, she was later revived post-conflict. Following a global repetrification, Yuzuriha repainted her old petrification scars as symbols of resilience, vowing removal only after neutralizing the Why-man threat. She collaborated with Kaseki on detailed scientific models and joined the expedition to America. Her journey culminated in marriage to Taiju after the Kingdom of Science resolved the petrification crisis, her hair regrown to its original length. Yuzuriha consistently displayed kindness, loyalty, and quiet determination, prioritizing others' safety—pleading with Senku not to reveal the formula while Tsukasa held her hostage. Her intelligence detected deception, like Senku's false claims about U.S. military aid or Gen's schemes. Reserved yet mentally resilient, she maintained consciousness for eight years during petrification by emulating Senku's time-tracking method. Her tailoring mastery extended beyond repairs to creative expression, earning the nickname "wild beast" for her intense focus and speed. She endured lengthy scientific lectures, retaining complex information like rocket science. Her dedication to restoring petrified individuals reflected her compassionate belief in humanity's potential.