Misae Nohara, born Misae Koyama, is a 29-year-old housewife from Aso, Kumamoto, balancing household duties with unpredictable shifts between meticulous effort and casual neglect. She enforces strict rules on her husband Hiroshi and son Shinnosuke but often undermines her own mandates, justifying extravagant shopping sprees as "budget-saving" ventures while stockpiling impractical sale items. Her disciplinary tactics feature theatrically physical flair, from the head-drilling "Guri-Guri Attack" to the cartoonishly forceful "Genkotsu Scene," occasionally even targeting her toddler daughter Himawari. Though frugal with Hiroshi and Shinnosuke, she indulges in luxury purchases for herself and Himawari, though these often meet chaotic fates at her children’s hands.  
Privately insecure about her weight and petite figure, she fixates on Hiroshi’s interactions with other women, once trailing him on a business trip in misplaced suspicion of infidelity. She covertly stashes personal savings, though these funds inevitably dissolve into family crises. A bizarre incident saw her accidentally ingest a transformative liquid, morphing into a memory-wiped leopardess who attacked Shinnosuke before recovering her identity and helping foil a plot to erase human memories via animalization.  
Notoriously distracted behind the wheel, her driving frequently ends in minor collisions. She bonds closely with sisters Masae and Musae Koyama and dabbles in part-time work, though her volatile temper and sporadic outbursts curb steady employment. Despite frequent clashes with Hiroshi over finances and domestic priorities, their marriage reveals flickers of mutual care beneath the friction. Occasional acts of quiet generosity—like covertly alleviating family financial burdens—hint at layers beneath her mercurial exterior.