"Amaenaideyo!! MS" is a comedic supernatural manga series that serves as a sequel to "Amaenaideyo!!" and continues the story of the young monk Ikkou Satonaka and the group of novice nuns at the Saienji Temple. The narrative revolves around Ikkou, who possesses a unique ability to summon a powerful Buddhist deity when exposed to extreme arousal. This ability often leads to chaotic and humorous situations, as the nuns at the temple are tasked with keeping his emotions in check to prevent unintended summonings.

The series introduces new characters and expands on the dynamics of the existing cast. Ikkou's interactions with the nuns—Sumi Ikuina, Haruka Amanogawa, Kazuki Yokogawa, Tomo Yamanobe, and Chitose Nanbu—drive much of the plot. Each nun has distinct personalities and quirks, contributing to the comedic and sometimes dramatic tension. The temple's abbess, Chitose's grandmother, oversees the group and often assigns them missions to deal with supernatural disturbances, which serve as the primary episodic conflicts.

The overarching plot involves the nuns and Ikkou confronting various supernatural entities, often tied to Buddhist mythology or local legends. These encounters are interspersed with slice-of-life moments that highlight the characters' relationships and personal growth. The series balances humor, action, and lighthearted romance, with Ikkou's feelings for the nuns, particularly Sumi, adding a layer of romantic tension. The narrative maintains a light tone, focusing on comedic misunderstandings and the absurdity of Ikkou's predicament, while occasionally delving into more serious themes of duty, spirituality, and camaraderie.

As the story progresses, the characters face increasingly challenging situations, testing their abilities and bonds. The series concludes with a mix of resolution and open-endedness, leaving room for further adventures while providing satisfying closure to key character arcs. "Amaenaideyo!! MS" builds on its predecessor's foundation, offering a blend of supernatural action, comedy, and character-driven storytelling.