"100nen Tattara Minna Shinu" is a manga series that blends elements of fantasy, mystery, and psychological drama. The narrative centers on a group of individuals who find themselves trapped in a mysterious, isolated village where time behaves abnormally. The villagers are cursed with immortality, unable to die or age, but this immortality comes with a grim condition: if they remain in the village for 100 years, they will all perish simultaneously. The story explores the psychological and emotional toll of this curse as the characters grapple with their predicament and search for a way to escape their fate.

The protagonist, a young man named Shun, arrives in the village under unclear circumstances and quickly becomes entangled in the lives of its inhabitants. He discovers that the village operates under a set of strict rules, enforced by a mysterious figure known as the "Keeper." The Keeper ensures that no one leaves the village and that the curse remains intact. As Shun interacts with the villagers, he learns about their pasts, their struggles with immortality, and their desperate attempts to break the curse. Among the key characters are Aoi, a girl who has lived in the village for decades but retains the appearance of a child, and Ren, a man who has grown weary of his endless existence and seeks meaning in his life.

The plot unfolds through a series of interconnected arcs, each revealing more about the village's history, the origins of the curse, and the true nature of the Keeper. The villagers' attempts to escape or alter their fate often lead to tragic consequences, highlighting the futility of their efforts. The story delves into themes of mortality, the passage of time, and the human desire for freedom and purpose. As Shun uncovers the village's secrets, he must confront his own fears and motivations, ultimately playing a pivotal role in the villagers' struggle against their cursed existence. The manga maintains a tense, atmospheric tone, with its narrative driven by the characters' emotional journeys and the ever-present threat of their impending doom.