In a decaying, impoverished town cut off from any major city, a group of young girls survives by any means necessary. Chanel, a cheerful and largely illiterate elementary-school dropout, lives with her mother and younger sister in a nearly empty house. She and her best friend Chihiro belong to Kurea's crew, a semi-organized criminal group that controls the east side of town. Their main hustle is cultivating and selling marijuana, and they occasionally run jobs involving assault, theft, and drug peddling. The west side is run by Shizuka, a yakuza ex-con and Kurea's unstable childhood friend, who tries to destabilize the uneasy truce between the two factions by flooding the area with a new synthetic drug called Balloon.

The town itself is a place where violence, drug addiction, poverty, and discrimination are woven into everyday life. Chanel and Chihiro scavenge cigarette butts, eat stolen convenience-store discarded bento as a treat, and sell trinkets like single shoes or polished ten-yen coins at a flea market known as Thief Market. Despite the grim conditions, the girls genuinely believe their hometown is the best place in the world, a conviction that both comforts and traps them. Their ignorance of life beyond the town limits is both their shield and their curse.

The story follows Chanel as she drifts deeper into Kurea's world, guided by the gruff but instructive senior Koharu. Chihiro falls into addiction after trying Shizuka's Balloon, then endures a harsh two-week confinement to sober up under Kurea's orders. Meanwhile, the town's instability escalates. A rogue, unpredictable fighter known only as Maru-chan operates outside any gang's control. Older figures from the criminal underworld, such as Yuna-chii and Momoka, enter the fray as power struggles intensify. A corrupt but effective police detective named Nara and her mentor, the ruthless station chief Hakusan, begin a crackdown on the town's gangs, further tightening the pressure. Later arcs introduce the genuine yakuza organization Kyokuseikai, whose enforcer Kirara brings a new level of professional brutality, and a planned large-scale commercial redevelopment that threatens to displace everyone. The girls are caught between police sweeps, yakuza incursions, and their own destructive loyalties.

Throughout the series, the contrast between the cute, soft art style and the harsh, often brutal content is central. The characters commit and suffer violence without glamorization, and the dialogue is laced with slang and real-world references. For all the misery, Chanel and her friends cling to each other, to their routines, and to the idea that their hometown, however broken, is still the only home they have.